Do Digium telephony cards support SS7-TDM INAP Protocol?
Protocols supported by our Telephony cards are dependent on Asterisk. If the Asterisk version implemented on your system supports the signaling that you are interested in, your telephony card should be able to use it.
Digium Technical support does not provide support for SS7 implementation. Asterisk has limited support for SS7 signaling and you are free to use Digium cards with this signaling.  if you are looking for assistance, please contact the Asterisk Community http://forums.asterisk.org/
If you are looking for information about Digium supported signaling please check  Telephony Cards Datasheet
https://www.digium.com/sites/digium/files/telephony-cards-datasheet.pdf